This is a nice, not ridiculously high-dosed capsule preparation of DIM with antioxidant extracts in a rice flour base. Capsule is easy to swallow with a smooth texture, if a little large, and it seems to do its job based on subjective experience. I am always reluctant to praise the efficacy of any supplement in reviews, because experiences are so individual and this is always something your health care provider should be more involved with than some fox on the Internet. I can tell you that I tolerate this preparation well, and so far as I can tell it’s identical to one sold by a higher-priced boutique brand. Wholesome Story’s inositol preparation was also effective for me, so between this and the DIM I’m inclined to trust them for hormonal assistance.
One daily capsule with 150 mg of DIM plus pomegranate, broccoli seed and black pepper extracts. A source of antioxidants.* DIM is short for diindolylmethane. It is the compound your body forms from broccoli, kale and other cruciferous vegetables.*
- Supports healthy estrogen metabolism.*
- DIM is the compound your body forms from broccoli, kale and other cruciferous vegetables.*
- A source of antioxidants.*
- With pomegranate, a source of polyphenol antioxidants.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
| Serving Size | 1 Capsule |
|---|---|
| Servings Per Container | 60 |
| Amount Per Serving | |
| Diindolylmethane (DIM) | 150 mg** |
| Pomegranate (Punica granatum) Fruit Extract | 100 mg** |
| Broccoli Seed Extract (Sulforaphane glucosinolate) (Brassica oleracea italica) | 25 mg |
| Organic Black Pepper (Fruit) Extract (Std. to 10% Piperine) | 2.5 mg** |
| **Daily Value (DV) not established. | |
| Other Ingredients | Rice Flour, Hypromellose (Capsule). |
DIM with Pomegranate Extract + Broccoli Seed Extract + Black Pepper Extract
One daily capsule with 150 mg of DIM plus pomegranate, broccoli seed and black pepper extracts. A source of antioxidants.*
What customers say
308 ratings and reviews
89% rated 4 or 5 stars
59 written reviews. Featured reviews come first. Tap a star row or change the sort to see every rating, including the lowest.
I like the formulation with the pomegranate and black pepper extract, and so far seems like it's doing well and no side effects. I started taking DIM off and on for the last half year, I'll do a bottle and then rest a bit, and then do another bottle. Mainly I like it because we have so much plastics exposure, and I try to minimize but it comes from so many sources (including the bottle of these supplements LOL!) So this is a positive way I help my system to manage those estrogens from the plastics. I'm also perimenopausal so it's good to have hormonal support for that reason, too, these days. After the bottle is open you may notice a sulfur odor, which would be normal. So far, mine doesn't have that yet but like I said it's only been open a few days. The energy of this formula feels really good and it seems like a good addition to my nutritional supplement regimen.
I take DIM every day to help keep my hormones balanced and I can tell when I miss a day. I wanted these because they have good ingredients including pomegranate extract. I like pomegranate because for some reason, it just makes me feel good but there are actual tangible benefits too, as it is an antioxidant. These capsules also contain broccoli seed extract and black pepper powder which helps with absorption. Given the apparent care with which they’re made, I’m happy with the quality and so far they seem to be working fine with no negative effects.
The capsules look pure and uniform in color. They are easy to swallow, have no aftertaste, and no upset stomach. DIM is great for regulating estrogen in older men and women. This one has addition pomengranate extract and black pepper to give it an extra kick. I hope this review is helpful for you!
I used DIM supplements from the other companies and don't feel any difference betweenthis and others, but this one has pomegranate and broccoli extract, which add some more antioxidants. It's easy to swallow, no side effects. The price is pretty reasonable.
I’ve been using this to help regulate (and lower) estrogen. I’ve recently changed to increase the amount, but I feel like these worked better, so I’ll be switching back when I use what I currently have.
Reviews are the personal opinions and experiences of individual customers. Wholesome Story did not pay or reward anyone for them, and we do not edit them. They are not our claims. Wholesome Story products are not intended to diagnose, treat, cure, or prevent any disease, and individual results vary.
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How our customers take it.
Out of every 10 orders for our DIM, 7 are reorders.
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Half of the customers who reorder are still ordering into Sep. 1 in 4 go on past month 21.
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Based on real orders from our customers, on Amazon and on our store, as of October 2026.
Learn the basics
What is in this formula?
This formula pairs DIM, a compound formed from cruciferous vegetables, with pomegranate, broccoli seed and black pepper extracts.
In three steps
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Fruit, seed and pepper
The three extracts come from pomegranate fruit, broccoli seed and black pepper fruit.
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Soaked, then dried
NIH explains that an extract is made by soaking a plant in a liquid and often drying it.
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Blended with 150 mg DIM
Each capsule holds 150 mg of DIM with the three extracts.
| Name | DIM with Pomegranate Extract + Broccoli Seed Extract + Black Pepper Extract |
|---|---|
| Type of substance | DIM is an indole compound. The other three active ingredients are plant extracts. |
| Source | Extracts: pomegranate (Punica granatum), broccoli (Brassica oleracea italica) and organic black pepper. |
| Part used | Pomegranate: fruit. Broccoli: seed. Black pepper: fruit. DIM: does not apply. |
| Form in our product | A powder blend in a capsule. The black pepper extract is standardized to 10% piperine. The broccoli seed extract is named as sulforaphane glucosinolate. |
| Amount per serving (1 capsule) | DIM 150 mg. Pomegranate fruit extract 100 mg. Broccoli seed extract 25 mg. Organic black pepper fruit extract 2.5 mg. |
| Serving and bottle | 1 capsule is 1 serving. A bottle has 60 servings. |
| Daily Value | Not established |
| Other ingredients | Rice flour, hypromellose (capsule) |
| Capsule size and color | Size 0 (0.84 in long, 0.29 in wide). Clear vegetarian capsule with a sandy tan fill. |
Questions and answers
Where are these ingredients found in food?
All four ingredients trace back to foods people eat. DIM forms from a compound in broccoli, Brussels sprouts, cabbage, cauliflower and kale. The juicy seed coverings of pomegranate are eaten fresh, and black pepper is one of the earliest known spices. Broccoli sprouts hold 10 to 100 times more glucoraphanin by weight than mature broccoli.
Where do the names come from?
Pomegranate comes from Anglo-French words that mean seedy fruit. Broccoli is Italian, from a word for the flowering top of a cabbage. Piperine comes from piper, the Latin word for pepper. Diindolylmethane describes the molecule: two indole units joined through one carbon.
What do researchers study about these ingredients?
Researchers have studied how DIM is absorbed and changed in the body after oral doses. They have studied how glucoraphanin from broccoli seed extract turns into sulforaphane. They have studied how piperine affects the way the gut absorbs other compounds. They have studied which pomegranate compounds reach the blood and urine.
DIM
What is DIM?
DIM is short for 3,3'-diindolylmethane, a compound in the indole family. Its molecule is two indole units joined through one carbon atom. It comes from compounds in cruciferous vegetables such as broccoli and kale. Cruciferous vegetables are the cabbage and mustard family of plants.
4 more questions about DIM
Where does DIM come from?
In nature, DIM forms in the stomach after a person eats cruciferous vegetables. These vegetables hold a compound called glucobrassicin. Chopping or chewing breaks it down to indole-3-carbinol, and stomach acid joins that into DIM.
What does our DIM capsule look like?
Our capsule is clear with a sandy tan powder blend inside. Raw cruciferous vegetables get their sharp smell and bite from compounds called glucosinolates. DIM forms from one glucosinolate, called glucobrassicin.
How much DIM is in our capsule?
Each capsule has 150 mg of diindolylmethane (DIM), and one capsule is one serving. DIM has no established Daily Value. The other ingredients are rice flour and hypromellose, which forms the capsule.
How does the body take in and clear DIM?
The body takes in DIM from the gut and then changes it into other compounds. In one human study, DIM and several changed forms appeared in both blood and urine. After people took indole-3-carbinol, the DIM it formed was gone from the blood within 24 hours.
pomegranate fruit extract
What is pomegranate fruit extract?
Pomegranate fruit extract is a concentrated product made from the fruit of Punica granatum. An extract is made by soaking a plant in a liquid, such as water or alcohol. Pomegranate is a rich source of plant compounds called polyphenols. These include punicalagin, ellagic acid and anthocyanins.
4 more questions about pomegranate fruit extract
Where does pomegranate come from?
Pomegranate is the fruit of Punica granatum, a bush or small tree. Kew lists its native range as northeast Türkiye to west and north Pakistan. It is now grown around the Mediterranean, in Southeast Asia and in the southwestern United States.
What does pomegranate look and taste like?
A pomegranate is about the size of an orange, with a thick leathery skin. Inside are many seeds, each wrapped in juicy red pulp with a tart flavor.
How much pomegranate extract is in our capsule?
Each capsule has 100 mg of pomegranate (Punica granatum) fruit extract. It has no established Daily Value.
How does the body take in and clear pomegranate compounds?
Gut microbes break down large pomegranate compounds into smaller ones called urolithins. In one study of 16 healthy adults, ellagic acid was measured in blood after pomegranate juice or extract. A urolithin compound was then measured in the urine.
broccoli seed extract
What is broccoli seed extract?
Broccoli seed extract is a concentrated product made from the seeds of broccoli. We name it sulforaphane glucosinolate on our label, which is another name for glucoraphanin. Glucosinolates are sulfur-containing compounds found in cruciferous vegetables. Glucoraphanin is the compound that sulforaphane is formed from.
4 more questions about broccoli seed extract
Where does broccoli come from?
Broccoli is a form of cabbage in the mustard family, grown for its flower buds and stalk. Britannica describes it as native to the eastern Mediterranean and grown in Italy since ancient Roman times. Broccoli seeds hold glucoraphanin, and the amount stays about the same as they sprout and grow.
What gives broccoli its smell and taste?
Cruciferous vegetables get a sharp smell and a spicy or bitter taste when their cells are damaged. Damage, such as chopping or chewing, lets myrosinase, an enzyme, reach the glucosinolates. Enzymes are proteins that speed up reactions; this one makes the compounds behind the smell and taste.
How much broccoli seed extract is in our capsule?
Each capsule has 25 mg of broccoli seed extract from Brassica oleracea italica. We name the extract sulforaphane glucosinolate on our label.
How does the body take in and clear glucoraphanin?
Glucoraphanin must first be changed into a compound called sulforaphane. The plant enzyme myrosinase does this, and gut bacteria can do it too. The liver then joins sulforaphane to glutathione, a small molecule found in body tissues. The products leave the body in urine.
black pepper fruit extract
What is black pepper fruit extract?
Black pepper fruit extract is a concentrated product made from the fruit of the pepper vine. Black pepper is the spice made from the fruits of Piper nigrum, a climbing vine. Our extract is standardized to 10% piperine. Piperine is an alkaloid, a nitrogen-containing plant compound, with the formula C17H19NO3.
4 more questions about black pepper fruit extract
Where does black pepper come from?
Black pepper comes from the fruits of a woody climbing vine. Britannica says it is native to the Malabar Coast of India; Kew lists Sri Lanka as its native range. The fruits are picked as they begin to turn red, dipped in boiling water and dried in the sun. Our extract is organic.
What does piperine look, taste and smell like?
Pure piperine forms crystals that sources describe as nearly colorless to light yellow. It has an aroma like pepper. Britannica says the flavor of black pepper comes mainly from piperine. The taste of black pepper is hot and biting.
How much black pepper extract is in our capsule?
Each capsule has 2.5 mg of organic black pepper fruit extract. The extract is standardized to 10% piperine. Standardized means the maker measures a marker compound so batches are similar. It has no established Daily Value.
How does the body take in and clear piperine?
In rats, the gut absorbs about 97% of a piperine dose. The rat body then changes piperine chemically before it leaves the body. In one human study, almost no unchanged piperine was found in urine.
Sources (31)
We read these pages to write this tab. Each link opens in a new tab.
- Vermillion Maier 2021, Drug Metabolism and Disposition (PubMed)
- PubChem, 3,3'-Diindolylmethane (CID 3071)
- NIH Office of Dietary Supplements, Botanical Dietary Supplements Background Information
- Linus Pauling Institute, Indole-3-Carbinol
- Linus Pauling Institute, Cruciferous Vegetables
- Merriam-Webster, cruciferous
- Merriam-Webster, extract
- Seeram 2008, Journal of Medicinal Food (PubMed)
- Shetty 2026, Nutrition Reviews (PubMed)
- Britannica, pomegranate
- Kew, Plants of the World Online, Punica granatum
- NCCIH (NIH), Pomegranate
- Merriam-Webster, pomegranate
- Linus Pauling Institute, Isothiocyanates
- Britannica, broccoli
- Merriam-Webster, enzyme
- Zhu 2025, Food and Function (PubMed)
- Merriam-Webster, glutathione
- Britannica, black pepper
- PubChem, Piperine (CID 638024)
- Britannica, alkaloid
- Kew, Plants of the World Online, Piper nigrum
- Bhat 1986, Toxicology (PubMed)
- Itharat 2020, Research in Pharmaceutical Sciences (PubMed)
- Merriam-Webster, broccoli
- Merriam-Webster, piperine
- Anderton 2004, Drug Metabolism and Disposition (PubMed)
- Fahey 2019, Nutrients (PubMed)
- Khajuria 2002, Phytomedicine (PubMed)
- Shoba 1998, Planta Medica (PubMed)
- Wholesome Story product label and capsule guide
The short science, in plain words. This is background about the ingredients, not a claim about any product. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
- Size 0
- 0.84 in by 0.29 in
- 21 mm long
- 1 capsule a serving
- Sandy tan
| Active ingredients | DIM 150 mg, pomegranate fruit extract 100 mg, broccoli seed extract 25 mg, black pepper fruit extract 2.5 mg (standardized to 10% piperine) per capsule |
|---|---|
| Serving | 1 capsule a day, preferably with a meal |
| Bottle size | 60 capsules (60-day supply) |
| Other ingredients | Rice flour, hypromellose (capsule) |
| Capsule | Vegetarian capsule |
Take 1 capsule daily (1 serving), preferably with a meal, or as directed by a physician.
| Serving Size | 1 Capsule |
|---|---|
| Servings Per Container | 60 |
| Amount Per Serving | |
| Diindolylmethane (DIM) | 150 mg** |
| Pomegranate (Punica granatum) Fruit Extract | 100 mg** |
| Broccoli Seed Extract (Sulforaphane glucosinolate) (Brassica oleracea italica) | 25 mg |
| Organic Black Pepper (Fruit) Extract (Std. to 10% Piperine) | 2.5 mg** |
| **Daily Value (DV) not established. | |
| Other Ingredients | Rice Flour, Hypromellose (Capsule). |
Active Ingredients:
- Diindolylmethane (DIM)
- Pomegranate (Punica granatum) Fruit Extract
- Broccoli Seed Extract (Sulforaphane glucosinolate) (Brassica oleracea italica)
- Organic Black Pepper (Fruit) Extract (Std. to 10% Piperine)
Other Ingredients:
- Rice Flour, Hypromellose (Capsule)
Use only as directed. Consult your healthcare provider before use if you are contemplating pregnancy, pregnant, nursing, have any medical conditions, or use any medications. For adult use only. Keep this product out of reach of children. Do not use if tamper evident seal is broken or missing. Store in a cool, dry place.
These are published papers about the ingredients in this formula: how the body absorbs and uses them, and reviews of the research. Each one opens at PubMed. We list what each paper looked at, not what it proves. Many of the papers looked at lab or animal models, or at foods and doses that differ from our capsule. They are background reading, not claims about our products. Talk with your healthcare provider.
How the body absorbs and uses DIM
- A study in mice comparing how two DIM formulations were absorbed and spread to tissues after an oral dose.Anderton 2004, Drug metabolism and disposition (opens the paper)animal pharmacokinetic study
How the body absorbs and uses the ingredients
- A pilot study of how stomach acidity and enteric coating relate to the conversion of glucoraphanin from broccoli extract into sulforaphane.Fahey 2019, Nutrients (opens the paper)pilot clinical study
- A randomized study in 12 healthy adults of adding mustard seed to cooked broccoli and measuring a sulforaphane metabolite.Okunade 2018, Molecular nutrition & food research (opens the paper)randomized trial
- A laboratory model of digestion and absorption that tested how sulforaphane is made available from a glucoraphanin-rich broccoli seed extract.Zhu 2025, Food & function (opens the paper)laboratory (in vitro) study
- A laboratory study of piperine and how it changes properties of the intestinal membrane and enzyme activity.Khajuria 2002, Phytomedicine (opens the paper)laboratory (animal tissue) study
- A laboratory study in rat intestinal cells of piperine, amino acid uptake and the enzyme gamma-glutamyl transpeptidase.Johri 1992, Biochemical pharmacology (opens the paper)laboratory (animal cell) study
- A study in rats and healthy volunteers of piperine given together with curcumin and the resulting curcumin blood levels.Shoba 1998, Planta medica (opens the paper)animal and human pharmacokinetic study
Reviews of the evidence
- A review that discusses glucosinolates, the sulfur-containing plant compounds found in cruciferous vegetables.Capuano 2017, Current pharmaceutical design (opens the paper)narrative review
- An overview of herbal ingredients studied for their effects on how the body absorbs other substances.Kesarwani 2013, Asian Pacific journal of tropical biomedicine (opens the paper)narrative review
- A narrative review of pomegranate and its compounds, including punicalagin, ellagic acid, anthocyanins and urolithins.Shetty 2026, Nutrition reviews (opens the paper)narrative review
- A systematic review of pomegranate supplements in healthy adults, looking at exercise performance and recovery measures.Ammar 2018, British journal of nutrition (opens the paper)systematic review
Supplements you can trust.
The FDA does not test supplements before they are sold. So we ask independent groups to test ours. Each mark below says what it covers and what it does not.
- 90-day guarantee
- Blended in the USA with domestic and international ingredients
- American company
Clean Label Project CertifiedAn outside group tested this product for heavy metals, pesticides and plastic chemicals that labels do not list.
What it checks
- A brand sends a product to Clean Label Project. Independent labs screen it for heavy metals, pesticides (including glyphosate), phthalates and bisphenols.
- Clean Label Project judges each product on its own against limits set by product type.
- Clean Label Project says certified products are tested again every year.
What it does not mean
- It does not mean the product has zero contaminants. Clean Label Project notes heavy metals occur naturally.
- It does not check that the label amounts are correct. That is a different test.
NSF Certified Gluten-FreeNSF tested this product and audited where it is made to check it meets a gluten-free limit.
What it checks
- NSF reviews the ingredients and tests the finished product for gluten.
- NSF audits the manufacturing site to check that gluten cannot get into the product.
What it does not mean
- It does not mean the product treats or helps with any condition, including celiac disease.
- It covers gluten only. It does not cover other allergens or other claims.
More questions? We're here to help
What is DIM?
Diindolylmethane (DIM) is a compound your body forms when it digests cruciferous vegetables such as broccoli and kale. This product gives you 150 mg per capsule, together with pomegranate, broccoli seed and black pepper extracts.
What does each ingredient do in this formula?
DIM, pomegranate and broccoli seed extracts are plant-based ingredients that support your body's antioxidant defenses and cellular health.* Black pepper extract is added as a standardized source of piperine. See the ingredient cards in Learn the basics for plain-language descriptions of each one.
Is it safe? How is it taken?
Suggested use: Take 1 capsule daily (1 serving), preferably with a meal, or as directed by a physician.
Caution: Use only as directed. Consult your healthcare provider before use if you are contemplating pregnancy, pregnant, nursing, have any medical conditions, or use any medications. For adult use only. Keep this product out of reach of children. Do not use if tamper evident seal is broken or missing. Store in a cool, dry place.
Can I take it while pregnant or nursing?
Please do not decide on your own. Consult your healthcare provider before use if you are contemplating pregnancy, pregnant, or nursing.
Can I take it with other supplements or medicines?
Ask your healthcare provider first. This is most important if you take any medication or any other supplement.
In one study in women, DIM lowered the blood levels of tamoxifen, a prescription medicine. Please tell your healthcare provider about every medicine you take.
How long should I take it?
We cannot tell you how long to take it. Your healthcare provider can help you decide what is right for you.
What else is in the capsule?
The other ingredients are rice flour and hypromellose (the capsule). The capsules are vegetarian. Our products are made in a facility that also processes common food allergens, so we cannot promise the complete absence of any allergen unless it is listed on the label.
How many servings are in a bottle?
One capsule is one serving. A bottle has 60 capsules, so it has 60 servings. At 1 capsule a day, one bottle lasts 60 days.
Can I return it for a refund?
Yes. We offer a full refund on the purchase price minus shipping of our supplement products any time within 90 days (up to 3 bottles full or empty) for orders shipped in the United States. Please contact us through our Contact Us page for return instructions.
How big are the capsules?
Our DIM capsule is size 0, 0.84 inches by 0.29 inches, about as long as a US nickel is wide. One serving is 1 capsule.
Where people go next.
Here is what the customers who stay with us do next.
-
Most added Myo & D-Chiro Inositol is the product our DIM customers add most.From $27.95
Based on real orders from our customers.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Supply is based on the suggested use: 1 capsule a day. If your healthcare provider recommends a different dosage, your supply length may differ.