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Myo-Inositol & D-Chiro Inositol + MTHF Folate + Vitamin D3
Myo-Inositol & D-Chiro Inositol + MTHF Folate + Vitamin D3
Myo-Inositol & D-Chiro Inositol + MTHF Folate + Vitamin D3

Myo-Inositol & D-Chiro Inositol + MTHF Folate + Vitamin D3

120 Vegetarian Capsules 

A blend of 2,000mg of Myo-Inositol and 50mg of D-Chiro Inositol (following the body's normal ratio of 40:1) with added MTHF Folate and Vitamin D3 to support healthy hormone levels, menstrual cycles, ovarian health, and reproductive health.

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Support Your Monthly Well-Being and Reproductive Health
BENEFITS
SUGGESTED USE
CAUTION
Research

Supports Hormonal Health

Blood glucose control, reproductive support, ovarian support, hormone support, improved IVF outcomes.

Supports Healthy Fetal Development

Our product provides the recommended daily amounts of folate and vitamin D to support healthy development of the neural tube and associated structures during embryonic/fetal development and may even promote full-gestation births. 

Supports Bone Health and Insulin Sensitivity

The inositols and vitamin D can help pregnant and lactating women and older adults support their blood glucose levels and bone health by aiding in hormone balance and calcium absorption. 

Suggested Use:

For adults, take 4 capsules daily, preferably with a meal, or as directed by a physician. For those with a sensitive constitution, take 2 capsules twice daily.

Caution: 

Do not exceed recommended dose. Pregnant and nursing mothers, children under the age of 18, and individuals with a known medical condition or taking prescription medication should consult a physician before taking this or any dietary supplement.

[1] Williams, T., Mortada, R., & Porter, S. (2016). Diagnosis and treatment of polycystic ovary syndrome. American Family Physician, 94(2), 106-113. Retrieved from: https://www.aafp.org/afp/2016/0715/p106.html#sec-5

[2] Benelli, E., Del Ghianda, S., Di Cosmo, C., & Tonacchera, M. (2016). A combined therapy with myo-inositol and d-chiro-inositol improves endocrine parameters and insulin resistance in PCOS young overweight women. International Journal of Endocrinology. DOI: http://dx.doi.org/10.1155/2016/3204083

[3] Sortino, M. A., Salomone, S., Carruba, M. O., & Drago, F. (2017). Polycystic ovary syndrome: insights into the therapeutic approach with inositols. Journal Frontiers in Pharmacology, 8(341), 1-13. DOI: 10.3389/fphar.2017.00341

[4] Troisi, J., Cinque, C., Giugliano, L., Symes, S., Richards, S., Adair, D., Cavallo, P., Sarno, L., Scala, G., Caiazza, M., & Guida, M. (2019). Metabolomic change due to combined treatment with myo-inositol, d-chiro-inositol and glucomannan in polycystic ovarian syndrome patients: a pilot study. Journal of Ovarian Research, 12(25). DOI: https://doi.org/10.1186/s13048-019-0500-x 

[5] Kalra, B., Kalra, S., & Sharma, J. (2016). The inositols and polycystic ovary syndrome. Indian Journal of Ednocrinology and Metabolism, 20(5), 720-724. DOI: 10.4103/2230-8210.189231 

[6] Unfer, V., Facchinetti, F., Orru, B., Giordani, B., & Nestler, J. (2017). Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials. Endocrine Connections, 6(8), 647-658. DOI: 10.1530/EC-17-0243 

[7] Centers of Disease Control and Prevention. (2018, April 11). Folic acid. https://www.cdc.gov/ncbddd/folicacid/faqs/faqs-general-info.html

[8] Melitis, C. Folate vs. folic acid – facts about vitamin B. American Pregnancy Association. https://americanpregnancy.org/infertility/folate-vs-folic-acid-what-you-need-to-know/ 

[9] National Institutes of Health. (2020, March 11). Folate. https://ods.od.nih.gov/factsheets/Folate-HealthProfessional/ 

[10] Lynch, B. L-methylfolate, methylfolate, 5-MTHF, L-5-MTHF. What is the difference?! http://mthfr.net/l-methylfolate-methylfolate-5-mthf/2012/04/05/ 

[11] Stracquadanio, M., Ciotta, L., & Palumbo, M. A. (2018). Effects of myo-inositol, gymnemic acid, and L-methylfolate in polycystic ovary syndrome patients. Gynecological Endocrinology, 34(6), 495-501. DOI: 10.1080/09513590.2017.1418852 

[12] Scaglione, F., & Panzavolta, G. (2014). Folate, folic acid and 5-methyltetrahydrofolate are not the same thing. Xenobiotica, 44(5), 480-488. DOI: 10.3109/00498254.2013.845705 

[13] Obeid, R., Holzgreve, W., & Pietrzik, K. (2013). IS 5-methyltetrahydrofolate an alternative to folic acid for the prevention of neural tube defects? Journal of Perinatal Medicine, 41(5), 469-483. DOI: 10.1515/jpm-2012-0256 

[14] Fu, L., Dai, L., Li, X., Zhang, K., & Bai, Y. (2014). Association of methylenetetrahydrofolate reductase gene C677T polymorphism with polycystic ovary syndrome risk: a systematic review and meta-analysis update. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 172, 56-61. DOI: 10.1016/j.ejogrb.2013.10.001 

[15] Diwaker, A., & Kishore, D. (2018). Evaluation of plasma homocysteine levels in patients of PCOS. The Journal of the Association of Physicians of India, 66(10), 17-20. Retrieved from: https://pubmed.ncbi.nlm.nih.gov/31317701/?from_term=pcos+homocysteine&from_pos=1 

[16] Schachter, M., Raziel, A., Friedler, S., Strassburger, D., Bern, O., & Ron-El, R. (2003). Insulin resistance in patients with polycystic ovary syndrome is associated with elevated plasma homocysteine. Human Reproduction, 18(4), 721-727. DOI: 10.1093/humrep/deg190 

[17] Badawy, A., State, O., Sh Abd El Gawad, S., & Abd El Aziz, O. (2007). Plasma homocysteine and polycystic ovary syndrome: the missed link. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 131(1), 68-72. DOI: 10.1016/j.ejogrb.2006.10.015

 [18] Saadeh, N., Alfaqih, M. A., Mansour, H., Khader, Y. S., Saadeh, R., Al-Dwairi, A., & Nusier, M. (2018). Serum homocysteine is associated with polycystic ovary syndrome in Jordan. Biomedical Reports, 9(5), 439-445. DOI: 10.3892/br.2018.1149 

[19] Linus Pauling Institute. (2017, October). Vitamin D. https://lpi.oregonstate.edu/mic/vitamins/vitamin-D

[20] Harvard T.H. Chan School of Public Health. (2020, March). Vitamin D. https://www.hsph.harvard.edu/nutritionsource/vitamin-d/ 

[21] Krul-Poel, Y. H. M., Snackey, C., Louwers, Y., Lips, P., Lambalk, C. B., Laven, J. S. E., & Simsek, S. (2013). The role of vitamin D in metabolic disturbances in polycystic ovary syndrome: a systematic review. European Journal of Endocrinology, 169(6), 853-865. DOI: 10.1530/EJE-13-0617

[22] Krul-Poel, Y. H. M., Koenders, P. P., Steegers-Theunissen, R. P., Ten Boekel, E., Ter Wee, M. M., Louwers, Y., Lips, P., Laven, J. S. E., & Simsek, S. (2018). Vitamin D and metabolic disturbances in polycystic ovary syndrome (PCOS): a cross-sectional study. PLoS One, 13(12). DOI: 10.1371/journal.pone.0204748 

[23] He, C., Lin, Z., Robb, S. W., & Ezeamama, A. E. (2015). Serum vitamin D levels and polycystic ovary syndrome: a systematic review and meta-analysis. Nutrients, 7(6), 4555-4577. DOI: 10.3390/nu7064555 [24] Thomson, R. L., Spedding, S., Buckley, J. D. (2012). Vitamin D in the aetiology and management of polycystic ovary syndrome. Clinical Endocrinology, 77(3), 343-350. DOI: 10.1111/j.1365-2265.2012.04434.x 

[25] Dastorani, M., Aghadavod, E., Mirhosseini, N., Foroozanfard, F., Modarres, S. Z., Siavashani, M. A., & Asemi, Z. (2018). The effects of vitamin D supplementation on metabolic profiles and gene expression of insulin and lipid metabolism in infertile polycystic ovary syndrome candidates for in vitro fertilization. Reproductive Biology and Endocrinology, 16(1), 94. DOI: 10.1186/s12958-018-0413-3 

[26] Javed, Z., Papageorgiou, M., Deshmukh, H., Kilpatrick, E. S., Mann, V., Corless, L., Abouda, G., Rigby, A. S., Atkin, S. L., & Sathyapalan, T. (2019). Nutrients, 11(1), 188. DOI: 10.3390/nu11010188 

[27] Kagowska, K., Bajerska, J., & Jamka, M. (2018). The role of vitamin D oral supplementation in insulin resistance in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. Nutrients, 10(11), 1637. DOI: 10.3390/nu10111637

Core essential ingredients

Myo-Inositol

Part of the Vitamin B complex family, Myo-Inositol has been shown to promote female fertility through supporting hormone balance and ovarian function.

D-Chiro Inositol

D-Chiro Inositol balances the metabolic health especially for women with PCOS or insulin sensitivity. Our D-Chiro Inositol (Caronositol®) is a botanical extract purified from carob pods through a solvent-free patented process.

Vitamin D3 (Cholecalciferol) 

Vitamin D3 is organically produced in the body when the skin is exposed to UVB rays from the sun, which triggers its synthesis. Vitamin D3 can also be obtained from the diet in animal foods (fatty fish, egg yolk).

Folate (as L-5-Methyltetrahydrofolate or MTHF) 

MTHF is the predominant, natural and bioactive form of folate, or Vitamin B9. Both the synthetic form (folic acid) and the natural folate form (found in foods) are converted in the body to MTHF.

Customer Reviews

Based on 112 reviews
84%
(94)
8%
(9)
4%
(4)
2%
(2)
3%
(3)
K
Kelsey

It helps keep control on my blood sugar in addition to a healthy lifestyle.

J
Juliana hernandez
Wow 100% recommended!!!

I have being taking medication every month for years to induce my period along with metformin. I struggled with my period since I was 16 yrs old (I am 31 now) sometimes I wouldn’t get my period at all for years. I was diagnosed with PCOS at 16. So I decided to purchase this item I wasn’t too sure it will work since nothing else ever worked for me. I stop taking my doctors medication to induce my period because I wanted to see if this product will work. After taking it everyday for 3 months straight I finally got my period!!😀 No metformin no meds! Just this product!! This is my second month getting my period & I am so happy!😊 Not only I got my period but my cystic acne is under control! I couldn’t be more blessed! I just want to ask, does anyone know what vitamins I can take to get pregnant? My husband and I are struggling to get pregnant for 2 years now I was hoping someone can tell me what can I do to get pregnant? Or what should I take? 🙁

S
Samantha Weiss

Myo-Inositol & D-Chiro Inositol + MTHF Folate + Vitamin D3

A
Alexis
Works amazingly!

I have been doctor to doctor to try getting help for PCOS, metabolic and digestive issues. I have taken prescribed medications for years with no improvement. I started taking this when my nutritionist recommended it. While I still haven't gotten a period taking this for 30 days, I can say everything else has! I have been taking a daily laxative and other types of supplements because I normally only have a bowel movement a week, and since starting this I go every day and have even quit taking A LOT of my other supplements, including the laxatives. I also have more energy throughout the day (I now only drink 1 cup of coffee instead of 4) and am just more awake and for the first time in my life, finally feel like my age instead of an 80 year old. I will be buying more and subscribing for it to come every month!

J
Jelena Medeiros
Helped me with PCOS issues

Was having irregular periods, and sometimes no periods at all for months at a time and this has helped to get my cycle more normal. I have been taking this for almost 4 months now and I started noticing changes withing 2-3 weeks of starting it.

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