Myo-Inositol & D-Chiro Inositol

Name: Myo-Inositol & D-Chiro Inositol
Brand: Wholesome Story
SKU: WSS00001
Price: 25.95 USD
Availability: InStock

A supplement blend of 2,000 mg of Myo-Inositol and 50 mg of D-Chiro Inositol (following the body's normal ratio of 40:1) to support healthy hormone levels, menstrual cycles, and ovarian health.

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BENEFITS

SUGGESTED USE

CAUTION

Research

Supports Hormonal Health

Blood glucose control, reproductive support, ovarian support, hormone support, improved IVF outcomes.

Supports Your Menstrual Cycle

With healthier insulin sensitivity, it may help your body maintain healthy androgen, testosterone, and luteinizing hormone levels for a regular monthly cycle.

Supports Ovarian Health

Myo & D-Chiro Inositol are naturally occurring compounds found in plant foods which can support healthy ovulation, contribute to oocyte quality, and support overall reproductive and ovarian health.

Suggested Use:

Take 4 capsules (1 serving) daily, preferably with a meal, or as directed by a physician. For those with a sensitive constitution, take ½ of a serving (2 capsules) at once, twice per day.

Caution:

Use only as directed. Consult your healthcare provider before use if you are contemplating pregnancy, pregnant, nursing, have any medical conditions, or use any medications. For adult use only. Keep this product out of reach of children. Do not use if tamper evident seal is broken or missing. Store in a cool, dry place.

Please use caution when taking this product alongside any other supplement or medication that can lower blood sugar levels as this combination may increase the risk of hypoglycemia.

[1] Office of Population Affairs. (2019, February 21). Female infertility. https://www.hhs.gov/opa/reproductive-health/fact-sheets/female-infertility/index.html

[2] Cleveland Clinic. (2016, May 10). Infertility causes. https://my.clevelandclinic.org/health/diseases/16083-infertility-causes

[3] Lisi, F., Carfagna, P., Oliva, M. M., Rago, R., Lisi, R., Poverini, R., Manna, C., Vaquero, E., Caserta, D., Raparelli, V., Marci, R., & Moscarini, M. (2012). Pretreatment with myo-inositol in non polycystic ovary syndrome patients undergoing multiple follicular stimulation for IVF: a pilot study. Reproductive Biology and Endocrinology, 10(52), 1-7. http://www.rbej.com/content/10/1/52

[4] Kalra, B., Kalra, S., & Sharma, J. (2016). The inositols and polycystic ovary syndrome. Indian Journal of Ednocrinology and Metabolism, 20(5), 720-724. DOI: 10.4103/2230-8210.189231

[5] Benelli, E., Del Ghianda, S., Di Cosmo, C., & Tonacchera, M. (2016). A combined therapy with myo-inositol and d-chiro-inositol improves endocrine parameters and insulin resistance in PCOS young overweight women. International Journal of Endocrinology. DOI: http://dx.doi.org/10.1155/2016/3204083

[6] Sortino, M. A., Salomone, S., Carruba, M. O., & Drago, F. (2017). Polycystic ovary syndrome: insights into the therapeutic approach with inositols. Journal Frontiers in Pharmacology, 8(341), 1-13. DOI: 10.3389/fphar.2017.00341

[7] Papaleo, E., Unfer, V., Baillargeon, J.P., & Chiu, T.T. (2009). Contribution of myo-inositol to reproduction. European Journal of Obstetrics & Gynecology and Reproductive Biology, 147(2), 120-123. DOI: https://doi.org/10.1016/j.ejogrb.2009.09.008

[8] Carlomagno, G., Unfer, V., & Roseff, S. (2011). The D-chiro-inositol paradox in the ovary. Fertility and Sterility, 95(8), 2515-2516. DOI: 10.1016/j.fertnstert.2011.05.027

[9] Caprio, F., D’Eufemia, M.D., Trotta, C., Campitiello, M.R., Ianniello, R., Mele, D., & Colacurci, N. (2015). Myo-inositol therapy for poor-responders during IVF: a prospective controlled observational trial. Journal of Ovarian Research, 8. DOI: 10.1186/s13048-015-0167-x

[10] U.S National Library of Medicine. (2018, July 26). Spontaneous reproductive outcomes after oral inositol supplementation in infertile polycystic ovarian syndrome women. https://clinicaltrials.gov/ct2/show/NCT03598374

[11] Lagana, A.S., Rossetti, P., Buscema, M., La Vignera, S., Condorelli, R.A., Gullo, G., Granese, R., & Triolo, O. (2016). Metabolism and ovarian function in PCOS women: A therapeutic approach with inositols. International Journal of Endocrinology, 2016, 1-9. https://doi.org/10.1155/2016/6306410

[12] Reproductive Science Center. (2015, August 14). Myo-inositol for fertility treatment. https://rscbayarea.com/integrative-medicine-blog/myo-inositol-for-fertility-treatment

[13] Pundir, J., Psaroudakis, D., Savnur, P., Bhide, P., Sabatini, L., Teede, H., Coomarasamy, A., & Thangaratinam, S. (2017). Inositol treatment of anovulation in women with polycystic ovary syndrome: a meta-analysis of randomized trials. An International Journal of Obstetrics and Gynaecoloy, 299-308. DOI: 10.1111/1471-0528.14754

[14] Benelli, E., Del Ghianda, S., Di Cosmo, C., & Tonacchera, M. (2016). A combined therapy with myo-inositol and d-chiro-inositol improves endocrine parameters and insulin resistance in PCOS young overweight women. International Journal of Endocrinology, 2016. https://doi.org/10.1155/2016/3204083

[15] Gurevich, Rachel. (2019, September 21). Here’s why an FSH test is important for monitoring your fertility. https://www.verywellfamily.com/day-3-fsh-levels-test-1960172

[16] Bhide, P., Pundir, J., Gudi, A., Shah, A., Homburg, R., & Acharya, G. (2019). The effect of myo-inositol/di-chiro-inositol on markers of ovarian reserve in women with PCOS undergoing IVF/ICSI: A systematic review and meta-analysis. Obstetrics & Gynaecology, 98(10). https://doi.org/10.1111/aogs.13625

[17] U.S. National Library of Medicine. (2011, April 20). Role of myo-inositol and d-chiro-inositol on oocyte quality. https://clinicaltrials.gov/ct2/show/NCT01338844

[18] Colazingari, S., Treglia, M., Najjar, R., & Bevilacqua, A. (2013). The combined therapy myo-inositol plus d-chiro-inositol, rather than d-chiro-inositol, is able to improve IVF outcomes: results from a randomized controlled trial. Archives of Gynecology and Obstetrics, 288, 1405-1411. https://doi.org/10.1007/s00404-013-2855-3

Core essential ingredients

Myo-Inositol

Part of the Vitamin B complex family, Myo-Inositol has been shown to promote female fertility through supporting hormone balance and ovarian function.

D-Chiro Inositol

D-Chiro Inositol supports balanced metabolic health for women.

No period for over a year

I was on birth control for 10+ years. I finally got off the pill and did not have a period for over a year. Four months in, I went to the doctor and was diagnosed with PCOS. I had horrible acne, weight gain, low libido, and no periods. I started taking this and made some lifestyle changes (weight training, healthier diet, no dairy) and immediately my acne cleared up and I lost the weight. Finally, 14 months later, I got my period. I am still not regular but it defintely feels like a step in the right direction. I haven't felt this great in years! Obviously I cannot say whether this supplement is responsible for the change, but I think alongside other lifestyle changes, it is totally worth a try!

Very effective

My skin is clear and my blood sugar is balanced and period symptoms lessened

Inaccurate count

I just finished my third bottle and all of them have had 118 capsules instead of the 120 that are supposed to be in the bottle for 4 capsules/30 days serving. This is false advertisement. I really like the supplement and have noticed great improvement in my PMS symptoms; however, I am thinking of trying another brand due to this. I always end up 2 capsules short at the end.

Affected labs

Bump in Cr and LFTs- this was the only change I had made. Looked it up and it’s a possible side effect. Be wary and only use if you are able to monitor.

Seems to better quality…

I have used two other brands that offer the same ratio, but I do feel that the ones on wholesomestory is of higher quality, even though I think this brand is more focused towards women seeking to get pregnant and maybe not women struggling with PCOS. I feel they have a wide range of supplements that can help balance the hormonal, and emotional.

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