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  • Load image into Gallery viewer, Myo-Inositol & D-Chiro Inositol + MTHF Folate + Vitamin D3
  • Load image into Gallery viewer, Myo-Inositol & D-Chiro Inositol + MTHF Folate + Vitamin D3
Myo-Inositol & D-Chiro Inositol + MTHF Folate + Vitamin D3
Myo-Inositol & D-Chiro Inositol + MTHF Folate + Vitamin D3
Myo-Inositol & D-Chiro Inositol + MTHF Folate + Vitamin D3

Myo-Inositol & D-Chiro Inositol + MTHF Folate + Vitamin D3

120 Vegetarian Capsules 

Nourish your ovarian health with added methylfolate (MTHF) and Vitamin D3 on top of our perfect 40:1 ratio of Myo & D-Chiro Inositol blend.

90-day money-back guarantee

If you don’t see the desired results in 90 days, we promise you a full refund. No questions asked.

Regulate and rebalance your hormones with an added boost of nutrients
BENEFITS
SUGGESTED USE
CAUTION
Research

Improves metabolic profiles

If you have PCOS, your insulin levels tend to be imbalanced. Myo & D-Chiro Inositol can help improve insulin sensitivity to lower lipid and glucose levels, inflammation, blood pressure and risk for developing Type 2 diabetes and cardiovascular diseases.

Balances hormone levels

With the supplement’s positive effect on insulin resistance, your hormone levels can find its healthy balance again and you may see alleviated symptoms of PCOS such as unwanted facial hair, acne, and irregular periods.

Lowers homocysteine levels

PCOS women tend to have higher homocysteine levels which impacts insulin resistance and increases risk of cardiovascular diseases. MTHF regulates your homocysteine levels, especially beneficial if you have the MTHFR gene mutation.

Suggested Use:

For adults, take 4 capsules daily, preferably with a meal, or as directed by a physician. For those with a sensitive constitution, take 2 capsules twice daily.

Caution: 

Do not exceed recommended dose. Pregnant and nursing mothers, children under the age of 18, and individuals with a known medical condition or taking prescription medication should consult a physician before taking this or any dietary supplement.

[1] Williams, T., Mortada, R., & Porter, S. (2016). Diagnosis and treatment of polycystic ovary syndrome. American Family Physician, 94(2), 106-113. Retrieved from: https://www.aafp.org/afp/2016/0715/p106.html#sec-5

[2] Benelli, E., Del Ghianda, S., Di Cosmo, C., & Tonacchera, M. (2016). A combined therapy with myo-inositol and d-chiro-inositol improves endocrine parameters and insulin resistance in PCOS young overweight women. International Journal of Endocrinology. DOI: http://dx.doi.org/10.1155/2016/3204083

[3] Sortino, M. A., Salomone, S., Carruba, M. O., & Drago, F. (2017). Polycystic ovary syndrome: insights into the therapeutic approach with inositols. Journal Frontiers in Pharmacology, 8(341), 1-13. DOI: 10.3389/fphar.2017.00341

[4] Troisi, J., Cinque, C., Giugliano, L., Symes, S., Richards, S., Adair, D., Cavallo, P., Sarno, L., Scala, G., Caiazza, M., & Guida, M. (2019). Metabolomic change due to combined treatment with myo-inositol, d-chiro-inositol and glucomannan in polycystic ovarian syndrome patients: a pilot study. Journal of Ovarian Research, 12(25). DOI: https://doi.org/10.1186/s13048-019-0500-x 

[5] Kalra, B., Kalra, S., & Sharma, J. (2016). The inositols and polycystic ovary syndrome. Indian Journal of Ednocrinology and Metabolism, 20(5), 720-724. DOI: 10.4103/2230-8210.189231 

[6] Unfer, V., Facchinetti, F., Orru, B., Giordani, B., & Nestler, J. (2017). Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials. Endocrine Connections, 6(8), 647-658. DOI: 10.1530/EC-17-0243 

[7] Centers of Disease Control and Prevention. (2018, April 11). Folic acid. https://www.cdc.gov/ncbddd/folicacid/faqs/faqs-general-info.html

[8] Melitis, C. Folate vs. folic acid – facts about vitamin B. American Pregnancy Association. https://americanpregnancy.org/infertility/folate-vs-folic-acid-what-you-need-to-know/ 

[9] National Institutes of Health. (2020, March 11). Folate. https://ods.od.nih.gov/factsheets/Folate-HealthProfessional/ 

[10] Lynch, B. L-methylfolate, methylfolate, 5-MTHF, L-5-MTHF. What is the difference?! http://mthfr.net/l-methylfolate-methylfolate-5-mthf/2012/04/05/ 

[11] Stracquadanio, M., Ciotta, L., & Palumbo, M. A. (2018). Effects of myo-inositol, gymnemic acid, and L-methylfolate in polycystic ovary syndrome patients. Gynecological Endocrinology, 34(6), 495-501. DOI: 10.1080/09513590.2017.1418852 

[12] Scaglione, F., & Panzavolta, G. (2014). Folate, folic acid and 5-methyltetrahydrofolate are not the same thing. Xenobiotica, 44(5), 480-488. DOI: 10.3109/00498254.2013.845705 

[13] Obeid, R., Holzgreve, W., & Pietrzik, K. (2013). IS 5-methyltetrahydrofolate an alternative to folic acid for the prevention of neural tube defects? Journal of Perinatal Medicine, 41(5), 469-483. DOI: 10.1515/jpm-2012-0256 

[14] Fu, L., Dai, L., Li, X., Zhang, K., & Bai, Y. (2014). Association of methylenetetrahydrofolate reductase gene C677T polymorphism with polycystic ovary syndrome risk: a systematic review and meta-analysis update. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 172, 56-61. DOI: 10.1016/j.ejogrb.2013.10.001 

[15] Diwaker, A., & Kishore, D. (2018). Evaluation of plasma homocysteine levels in patients of PCOS. The Journal of the Association of Physicians of India, 66(10), 17-20. Retrieved from: https://pubmed.ncbi.nlm.nih.gov/31317701/?from_term=pcos+homocysteine&from_pos=1 

[16] Schachter, M., Raziel, A., Friedler, S., Strassburger, D., Bern, O., & Ron-El, R. (2003). Insulin resistance in patients with polycystic ovary syndrome is associated with elevated plasma homocysteine. Human Reproduction, 18(4), 721-727. DOI: 10.1093/humrep/deg190 

[17] Badawy, A., State, O., Sh Abd El Gawad, S., & Abd El Aziz, O. (2007). Plasma homocysteine and polycystic ovary syndrome: the missed link. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 131(1), 68-72. DOI: 10.1016/j.ejogrb.2006.10.015

 [18] Saadeh, N., Alfaqih, M. A., Mansour, H., Khader, Y. S., Saadeh, R., Al-Dwairi, A., & Nusier, M. (2018). Serum homocysteine is associated with polycystic ovary syndrome in Jordan. Biomedical Reports, 9(5), 439-445. DOI: 10.3892/br.2018.1149 

[19] Linus Pauling Institute. (2017, October). Vitamin D. https://lpi.oregonstate.edu/mic/vitamins/vitamin-D

[20] Harvard T.H. Chan School of Public Health. (2020, March). Vitamin D. https://www.hsph.harvard.edu/nutritionsource/vitamin-d/ 

[21] Krul-Poel, Y. H. M., Snackey, C., Louwers, Y., Lips, P., Lambalk, C. B., Laven, J. S. E., & Simsek, S. (2013). The role of vitamin D in metabolic disturbances in polycystic ovary syndrome: a systematic review. European Journal of Endocrinology, 169(6), 853-865. DOI: 10.1530/EJE-13-0617

[22] Krul-Poel, Y. H. M., Koenders, P. P., Steegers-Theunissen, R. P., Ten Boekel, E., Ter Wee, M. M., Louwers, Y., Lips, P., Laven, J. S. E., & Simsek, S. (2018). Vitamin D and metabolic disturbances in polycystic ovary syndrome (PCOS): a cross-sectional study. PLoS One, 13(12). DOI: 10.1371/journal.pone.0204748 

[23] He, C., Lin, Z., Robb, S. W., & Ezeamama, A. E. (2015). Serum vitamin D levels and polycystic ovary syndrome: a systematic review and meta-analysis. Nutrients, 7(6), 4555-4577. DOI: 10.3390/nu7064555 [24] Thomson, R. L., Spedding, S., Buckley, J. D. (2012). Vitamin D in the aetiology and management of polycystic ovary syndrome. Clinical Endocrinology, 77(3), 343-350. DOI: 10.1111/j.1365-2265.2012.04434.x 

[25] Dastorani, M., Aghadavod, E., Mirhosseini, N., Foroozanfard, F., Modarres, S. Z., Siavashani, M. A., & Asemi, Z. (2018). The effects of vitamin D supplementation on metabolic profiles and gene expression of insulin and lipid metabolism in infertile polycystic ovary syndrome candidates for in vitro fertilization. Reproductive Biology and Endocrinology, 16(1), 94. DOI: 10.1186/s12958-018-0413-3 

[26] Javed, Z., Papageorgiou, M., Deshmukh, H., Kilpatrick, E. S., Mann, V., Corless, L., Abouda, G., Rigby, A. S., Atkin, S. L., & Sathyapalan, T. (2019). Nutrients, 11(1), 188. DOI: 10.3390/nu11010188 

[27] Kagowska, K., Bajerska, J., & Jamka, M. (2018). The role of vitamin D oral supplementation in insulin resistance in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. Nutrients, 10(11), 1637. DOI: 10.3390/nu10111637

Core essential ingredients

Myo-Inositol

Part of the Vitamin B complex family, Myo-Inositol has been shown to promote female fertility through supporting hormone balance and ovarian function.

D-Chiro Inositol

D-Chiro Inositol balances the metabolic health especially for women with PCOS or insulin sensitivity. Our D-Chiro Inositol (Caronositol®) is a botanical extract purified from carob pods through a solvent-free patented process.

Vitamin D3 (Cholecalciferol) 

Vitamin D3 is organically produced in the body when the skin is exposed to UVB rays from the sun, which triggers its synthesis. Vitamin D3 can also be obtained from the diet in animal foods (fatty fish, egg yolk).

Folate (as Methylfolate or MTHF) 

MTHF is the predominant, natural and bioactive form of folate, or Vitamin B9. Both the synthetic form (folic acid) and the natural folate form (found in foods) are converted in the body to MTHF.

Customer Reviews

Based on 29 reviews
79%
(23)
17%
(5)
3%
(1)
0%
(0)
0%
(0)
E
E.
Beyond thrilled!

A few years ago I suffered from a large ovarian cyst, and after it ruptured my hormone levels and ovulation never felt the same. I gained a ton of weight, my libido diminished, and no physician/OB-GYN would take the time of day to help me figure out the issue. Both said it could be due to age, even though this occurred from age 25 to my current age of 28. I work in the medical field and decided to dig deep into the medical research for this and read a lot about myo-inositol, so I decided to give it a shot. I've now been taking it for a month and WOW! My libido is back, I've lost 5 pounds, and it's given me the energy to start my favorite HIIT workout program again. I finally have the same 'ovulation rush' I used to get pre-cyst, where I feel on top of the world and extremely healthy. THIS PRODUCT IS AMAZING! This is truly a lifesaver, I feel like my former self again :)

K
K.B.

Myo-Inositol & D-Chiro Inositol + MTHF Folate + Vitamin D3

J
J.
One week and seeing changes

I started taking this because I read The Obesity code and started doing more research on insulin resistance which then led me down the PCOS path. I don't know if its been long enough, but I plucked my chin hairs a week ago and since I started taking this I haven't had any start growing back. I am usually plucking chin hairs every few days. I also had my period come back right away. I have Mirena BC and my period hasn't been regular in 6 years. I ran a half marathon and saw no weight loss. I eat better than anyone in my house and I weigh the most. I did a 1200 calorie diet, whole food, low carb for 4 months and saw zero changes. I have a membership at OrangeTheory and after I spent a few months working out there I noticed some days I would blow through the workout like a beast and others I was so completely exhausted I cried during sit ups. My friend took me on a 3 mile hike and I slept for four hours straight after. I am the 250 pound skier in Colorado because Im athletic, just a big girl. I can lift 50+ pounds with one arm and I am not a bodybuilder. Im just reaching a point where the Obesity Code has to be right, my hormones must be really off. Looking forward to seeing more changes as time goes.

M
M.
Well Alrighty Then

These pills are really good. I noticed a increase in my energy and drop a couple lbs... How Bout That 😊

S
S.V.
Pcos go to vitamin

Works amazingly, I've dropped 15 lbs in 4 weeks. I've never lost weight like this before. I feel great.

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